Glucose is aldohexose also known as dextrose, occuring as the D-form and found as a free monosaccharide in fruits and other plants and in the normal blood of all animals. Glucose is the chief source of energy for living organisms, its utilization is being controlled by insulin.
Glucose also known as Dextrose, Dextrose. . It is of Synthetic origin and belongs to Carbohydrate. It belongs to Parenteral Nutrition pharmacological group.The Molecular Weight of Glucose is 180.20.
Oral absorption of Glucose is found to be 100% . Volume of distribution is found to be 11.4-24.5 litre and plasma protien binding is negligible. Plasma half life is 43 min.
Glucose is known to interact with other drugs, the details of drug interactions is as follows:
Drug Details Severity Onset Management Cyanocobalamin Ispaghula Kanamycin (Acid Sulphate) Warfarin (Na)
These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interference in Pathology
No data regarding the pathological interferences produced by Glucose is available.
The severe or irreversible adverse effects of Glucose, which give rise to further complications include Anaphylactoid reactions, Seizures, Water intoxication, Diabetes mellitus.
Glucose produces potentially life-threatening effects which include Coma, Heart failure, Edema, Sodium retention. which are responsible for the discontinuation of Glucose therapy.
The symptomatic adverse reactions produced by Glucose are more or less tolerable and if they become severe, they can be treated symptomatically, these include Thrombophlebitis, Hypokalemia, Hypomagnesemia, Paresthesias, Hypophosphatemia, Vein irritation, Pain at injection site.
Click on the appropriate strength of the dosage form to view its available brands.
Single Ingredient Inj: 3.3 g, 5 %w/v, 10 %w/v, 25 %w/v, 5000 IU, Inj-IV: 5 %w/v, 25 %w/v, Inf: 5 g, 25 g, 5 %w/v, 10 %w/v, 25 %w/v, Soln: 5 %w/v, Multi ingredient
Inj: 5 %w/v, 4.3 %w/v, 8.25 %w/v, Inf: 5 g/L, 5 %w/v, 1.5 g/L, 10 %w/v, 1.5 %w/v, 3.3 %w/v, 4.25 g/L, 4.3 %w/v, 5 g/1000ml, 135 g/1000ml, 150 g/1000ml, 240 g/1000ml, 112.5 g/1000ml, Syrup: 10 g/500ml, 3.96 mg/5ml, Soln: 17 g/L, 5 %w/v, 10 g/500ml, 10 mg/500ml, 15 g/1000ml, Oral Soln: 20 g, 10 g/500ml, Liquid: 10 g/500ml, 100 mg/5ml, Sachet: 20 g, 13.5 g, 13.5 gm, 3.56 g/5.177, Powder: 20 g/Sachet,
Glucose's dosage details are as follows:
2.5 to 10 % 6.2 (6.25) As recommended. IV Inf As required
1000 mg/ kg/hr 1000 (1000) As recommended. IV Inf As Required
Paedriatic Dosage ( 20 Kg. )
No data regarding the Paedriatic dosage details of Glucose is available.
Neonatal Dosage ( 3 Kg. )
No data regarding the neonatal dosage details of Glucose is available.
High Risk Groups
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Warning / Precautions
Perform clinical evaluations and laboratory determination to monitor fluid balance, electrolytes concentration and acid-base balance. There may be the chances of hyperglycemia and glycosuria in such conditions slow the infusion rate monitor blood or urine glucose, if necessary administered insulin. When concentrated glucose infusion is abruptly withdrawn, administered 5% or 10% glucose.
Store in a well closed container, Below 25°C.
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