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Artemether is a derivative of artemisinin (herb found in china). Artemether is used for the treatment of malaria (intermittent or remittent diseases characterized by attacks of chills, fever, and sweating and caused by a parasitic protozoan transferred to the human bloodstream by an anopheles mosquito) in combination with other anti-malarial drugs resistant to conventional drugs.


Primary Characterstics

Molecular Structure of Artemether
. It is of Natural origin and belongs to Sesquiterpene lactone. It belongs to Antimalarial Agent pharmacological group.The Molecular Weight of Artemether is 298.40.


Volume of distribution is found to be 20 litre and plasma protien binding is 95.4%. and metabolism is reported liver. Plasma half life is 45 min.


Artemether is primarily indicated in conditions like Chloroquine resistant malaria, Complicated and severe malaria, Uncomplicated malaria.


Drug Interactions

Artemether is known to interact with other drugs, the details of drug interactions is as follows:

VORICONAZOLEAdditive QTc prolongation may occur.concomitant therapy should be avoided

These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Interference in Pathology

No data regarding the pathological interferences produced by Artemether is available.

Side Effects

The severe or irreversible adverse effects of Artemether, which give rise to further complications include Retinopathy, Neurotoxicity, QT prolongation.

Artemether produces potentially life-threatening effects which include Cardiovascular depression, Cardiopulmonary arrest. which are responsible for the discontinuation of Artemether therapy.

The signs and symptoms that are produced after the acute overdosage of Artemether include Vomiting, Convulsions, Coma, Cardiopulmonary arrest.

The symptomatic adverse reactions produced by Artemether are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Anorexia, Diarrhea, Fever, Insomnia, Tinnitus, Abdominal pain, Sleep disturbancesX, Rashes, Urticaria, Pruritus, Itching, Sleep disturbance, Hypotension, Elevation of liver enzymes, Transient low fever, Abnormal gait, parasthesia, Decreased hearing.

Available Brands

Click on the appropriate strength of the dosage form to view its available brands.

Single Ingredient

Inj: 40 mg/ml, 80 mg/ml,
Inj-IM: 80 mg,
Susp: 15 mg/5ml, 40 mg/5ml,
Tabs: 20 mg, 40 mg, 60 mg, 80 mg,
Caps: 20 mg, 40 mg, 80 mg,
Soft Caps: 40 mg,

Multi ingredient

Inj: 80 mg/ml,
Syrup: 15 mg/5ml,
Susp: 15 mg, 30 mg, 15 mg/5ml, 30 mg/5ml, 90 mg/5ml,
Dry Susp: 30 mg/5ml,
Cream: 0.08 %w/w,
Tabs: 20 mg, 40 mg, 80 mg,
Tabs DS: 40 mg,
Caps: 20 mg, 40 mg, 80 mg,


Artemether's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

160 mg160 (160)24 hourlyPO,IMInitial
80 mg80 (80)24 hourlyPO.IMMaintenance, As Required

Paedriatic Dosage ( 20 Kg. )

3.2 mg/kg3.2 (3.2)12 hourlyIntra MuscularFor 3 Days

Neonatal Dosage ( 3 Kg. )

No data regarding the neonatal dosage details of Artemether is available.

High Risk Groups

Drug should not be given to Pregnant Mothers, and Cardiac / Hypertensive Patients.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Warning / Precautions

Care should be taken when using to treat the women being pregnant with in three months or patients with severe vomiting. Administeration of Artemether with drugs that are metabolized by Cytochrome Enzyme CYP 2D6 like Flecainide,Metoprolol,Imipramine,Amitryptaline,Clomipramine should be avoided and artemether should also be avoided with drugs that prolong QT interval

Storage Conditions


Store in a well closed container, at room temperature, Below 30°C. Protect from Moisture.

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