Sign in or Sign up

User ID

Password

Remember me - forgot password

 

Sign up or Sign in

Name (in full)

Email address

Password

Confirm Password

 

Levetiracetam

Overview

Levetiracetam is an anti-epileptic drug which is used for the adjunctive treatment of partial seizures, with or without secondary generalisation.

Category:

Primary Characterstics

.

Pharmacokinetics

Oral absorption of Levetiracetam is found to be 50% ±50. Volume of distribution is found to be 0.6l/kg and plasma protien binding is <10%. Renal Excretion accounts for 66% and plasma half life is 7(6-8)hr.

Indications

Levetiracetam can be given in adjunctive therapy as an alternative drug of choice in Iron deficiency anaemia.

Contraindications

Levetiracetam is contraindicated in conditions like Breast feeding.

Drug Interactions

No data regarding the interactions of Levetiracetam was found.

Interference in Pathology

No data regarding the pathological interferences produced by Levetiracetam is available.

Side Effects

The symptomatic adverse reactions produced by Levetiracetam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Vertigo, Headache, Drowsiness, Ataxia, Anorexia, Nervousness, Rashes, Depression, Tremor, Asthenia, Aggression.

Available Brands

Click on the appropriate strength of the dosage form to view its available brands.

Single Ingredient

Inj: 500 mg/5ml,
Syrup: 100 mg/ml,
Soln: 100 mg/ml,
Oral Soln: 500 mg, 100 mg/ml,
Tabs: 1 g, 250 mg, 500 mg, 750 mg,

Dosage

Levetiracetam's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

1000 mg/day1000 (1000)As recommended.POAdditional dosing increments may be given (1000 mg/day additional every 2 weeks) to a maximum recommended daily dose of 3000 mg.

Paedriatic Dosage ( 20 Kg. )

No data regarding the Paedriatic dosage details of Levetiracetam is available.

Neonatal Dosage ( 3 Kg. )

No data regarding the neonatal dosage details of Levetiracetam is available.

High Risk Groups

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Warning / Precautions

Levetiracetam should be used with caution in patients with hepatic impairment (Halve dose in severe hepatic impairment due to cocomitant renal impairment); renal impairment (May need dose reduction a/c to creatinine clearance); pregnancy (use only if potential benefits outweighs risk); avoid sudden withdrawl.

Storage Conditions

comments powered by Disqus