Lansoprazole
Overview
Lansoprazole is an acid proton pump inhibitor. Lansoprazole is a benzimidazole sulfoxide derivarive and produces long lasting inhibition of gastric acid secretion. Lansoprazole is a chiral cmpound with one chiral center, synthsized as a racemic mixture and both enantiomers are active. Chemically Lansoprazole is identified as 2-[[[3-methyl-4-(2, 2, 2-trifluoroethoxy)-2-pyridinyl] methyl] sulfinyl ]-1H-benzimidazole. Lansoprazole is effective in the treatment of duodenal or gastric ulcer, gastroesophageal reflux disease and in the treatment of zollinger-ellison syndrome. Lansoprazole is administered orally.
Categories
- 17 Gastrointestinal drugs
- 17.1 Antacids/ Antiflatulents/ Antipeptic ulcerants
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Lansoprazole's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 15 to 30 mg | 22 (22.5) | 24 hourly | PO | Frequency may increased to twice.15 mg/day is given on an empty stomach. |
Paedriatic Dosage (20kg)
|
| 15 mg | 15 (15) | 24 hourly | | 30 mg or less. |
| 30 mg | 30 (30) | 24 hourly | | More than 30 kg |
Neonatal Dosage (3kg)
|
| | | | Not recommended in this age group |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Lansoprazole
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