Memantine
Overview
Memantine (HCl) is a derivative of amantadine. Similar to amantadine, it inhibits enzyme N-methyl-D-aspartate receptors, that affects glutamate transmission. Memantine (HCl) is used in the treatment of mild to moderate dementia in Alzheimer`s disease. Memantine (HCl) is also used in the management of Parkinsonism and cerebral spasticity.
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Memantine's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 5 mg | 5 (5) | 12 hourly | PO | Initially for 1 week. In morning. |
| 10 mg | 10 (10) | 24 hourly | PO | Maintenance In divided doses to maximum of 20 mg |
Paedriatic Dosage (20kg)
|
| No data regarding the Paedriatic dosage details of Memantine is available. |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Memantine is available. |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Memantine
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