Streptozotocin
Overview
Streptozotocin is antineoplastic antibiotic derived from Streptomyces achromogenes or produced by chemical synthesis. Streptozotocin is the drug of choice in the of treatment of malignant pancreatic insulinomas and malignant carcinoid tumors (especially when given along with Fluorouracil). Streptozotocin is also effective in the treatment of Hodgkin`s disease and for colon cancer, when used in combination with other anticancer drugs.
Categories
- 8 Antineoplastics, immunomodulators and drugs used in palliative care
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Streptozotocin's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 500 mg/sq.meter | 920 (916) | 24 hourly | IV | For 5 Days |
Paedriatic Dosage (20kg)
|
| No data regarding the Paedriatic dosage details of Streptozotocin is available. |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Streptozotocin is available. |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Streptozotocin
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Manufacturers of
Streptozotocin
in Pakistan
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