Mafenide Acetate
Overview
Mafenide Acetate is an antibacterial, belongs to sulphonamides. Mafenide Acetate is used topically to prevent bacterial colonisation and infection of burn wounds. Mefenide acetate is absorbed from burn sites, and systemic levels are produced. The drug and its metabolites cause metabolic acidosis, a side effect that limits its usefulness.
Categories
- 13 Dermatological drugs (topical)
- 13.2 Anti-infectives, topical
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
Mafenide Acetate produces potentially life-threatening effects which include Hynolytic Anaemia. which are responsible for the discontinuation of Mafenide Acetate therapy.
The symptomatic adverse reactions produced by Mafenide Acetate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Allergic reactions, Hyperventilation, Metabolic acidosis, Urinary alkalosis, Intense pain at sites of application, Loss of fluid by evaporation from the burn surface.
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Dosage
Mafenide Acetate's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 5 % | 5 (5) | As recommended. | Topical | Use under moist in burns. |
Paedriatic Dosage (20kg)
|
| No data regarding the Paedriatic dosage details of Mafenide Acetate is available. |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Mafenide Acetate is available. |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Mafenide Acetate
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Manufacturers of
Mafenide Acetate
in Pakistan
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