Cloxacillin
Overview
Cloxacillin is an isoxazolyl penicillin. Penicillin is derived directly or indirectly from strains of fungi of the genus Penicillium and other soil inhabiting fungi grown on special culture media. The structure of penicillin consists of a thiazolidine ring connected to a ß lactam ring, which is attached to a side chain. its use is limited to treatment of penicillinase-producing Staphylococcus aureus infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular interval of time throughout the day and night as prescribed. Cloxacillin (Na) is important to take the drug for the full time period as prescribed. If you discontinue the drug it may result in ineffective treatment.
Categories
- 6 Anti-infective drugs
- 6.2 Antibiotics, systemic
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Cloxacillin's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 250 mg | 250 (250) | 6 hourly | IM | |
| 500 mg | 500 (500) | 24 hourly | Intra Peritoneal | |
| 500 mg | 500 (500) | 6 hourly | IV (slow) | Over 3-4 min. |
| 500 mg | 500 (500) | 6 hourly | PO | |
Paedriatic Dosage (20kg)
|
| 12.5 to 25 mg/kg | 19 (18.75) | 6 hourly | Oral | - |
| 12.5 to 25 mg/kg | 19 (18.75) | 6 hourly | Slow IV | - |
Neonatal Dosage (3kg)
|
| 7.812 to 15.625 mg/kg | 12 (11.7185) | 6 hourly | oral | |
| 7.812 to 15.625 mg/kg | 12 (11.7185) | 6 hourly | Slow intravenous | |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Cloxacillin
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