Fluorescein
Overview
Fluorescein is a staining agent. Fluorescein is used as a test of pancreatc function and for the detection of damage to cornea.
Primary Characterstics
Indications
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Pharmacokinetics
Plasma protien binding is 85%. and metabolism is reported Hepatic. Renal Excretion accounts for major and plasma half life is <1 hr.
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Contraindications
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Drug Interactions
No data regarding the interactions of Fluorescein was found.
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Side Effects
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Dosage
Fluorescein's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 1 % | 1 (1) | As recommended. | Ophthalmic | As Required |
Paedriatic Dosage (20kg)
|
| 0.125 % | 0.12 (0.125) | As recommended. | Opthalmic | As Required |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Fluorescein is available. |
High Risk Groups
Drug should not be given to Pregnant Mothers, and Neonates.
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
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Warning / Precautions
Care must be taken to avoid extravasation during injection as the high pH of fluorescein solution can result in severe local tissue damage.Complications resulting from extravasation can cause severe pain in the arm for up to several hours.
Caution is to be exercised in patients with a history of allergy or bronchial asthma. An emergency tray should be available in the event of possible reaction to FLUORESCITE Injection 10%. Use only if the container is undamaged.
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Storage Conditions
Eye Drops, Inj
Store in a well closed container. Protect from Sunlight.
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Interference in Pathology
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Brands / Trade Names of
Fluorescein
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