Oxytocin

Overview

Oxytocin is a naturally occuring nonapeptide hormone secreted by the posterior pituitary. It can be extracted from pituitary glands of larger mammals and Oxytocin is prepared commercially by chemical synthesis. It binds to specific receptors in the uterus causing uterine contraction, perticularly when oestrogen levels are high, this action make it useful in the induction of labour when medically mediated. Oxytocin is also used to facilitate the milk-ejection reflex. Oxytocin is given parentrally.

Categories

  • 22 Obstetrics and gynecological preparations

Primary Characterstics

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Oxytocin's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

5 to 10 IU/min7.5 (7.5)As recommended.IV InfIV drip inf. of the 5% of D/W containing 1 IU Oxytocin per 100ml, Initial Inf. rate of 1-4 mU/min may be gradually increased upto max. 20mU/min

Paedriatic Dosage (20kg)

Not used in children

Neonatal Dosage (3kg)

Not used in this age group

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Oxytocin

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Manufacturers of Oxytocin in Pakistan

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