Oxytocin
Overview
Oxytocin is a naturally occuring nonapeptide hormone secreted by the posterior pituitary. It can be extracted from pituitary glands of larger mammals and Oxytocin is prepared commercially by chemical synthesis. It binds to specific receptors in the uterus causing uterine contraction, perticularly when oestrogen levels are high, this action make it useful in the induction of labour when medically mediated. Oxytocin is also used to facilitate the milk-ejection reflex. Oxytocin is given parentrally.
Categories
- 22 Obstetrics and gynecological preparations
- 22.1 Labor inducers/inhibitors
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Oxytocin's dosage details are as follows:
Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
5 to 10 IU/min | 7.5 (7.5) | As recommended. | IV Inf | IV drip inf. of the 5% of D/W containing 1 IU Oxytocin per 100ml, Initial Inf. rate of 1-4 mU/min may be gradually increased upto max. 20mU/min |
Paedriatic Dosage (20kg)
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| | | | Not used in children |
Neonatal Dosage (3kg)
|
| | | | Not used in this age group |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Oxytocin
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