Simethicone

Overview

Categories

Primary Characterstics

Indications

Simethicone is primarily indicated in conditions like Esophagitis, Flatulence, Gastric bloating, Gastrocardiac syndrome, Irritable bowel syndrome, Itchy dermatitis, Meteorism, Oesophagitis, Peptic ulcer, Postoperative gas pains, Skin irritations.

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Pharmacokinetics

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Contraindications

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Drug Interactions

Simethicone is known to interact with other drugs, the details of drug interactions is as follows:

Severity N/A

Alginic Acid

Interaction of Alginic Acid with Simethicone

Details: This interaction is sometimes beneficial and sometimes may pose threats to life.
Management: Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Aluminium Hydroxide and Oxide

Interaction of Aluminium Hydroxide and Oxide with Simethicone

Details: This interaction is sometimes beneficial and sometimes may pose threats to life.
Management: Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Moderate

Strontium-89 Chloride

Interaction of Strontium-89 Chloride with Simethicone

Details: Saturation of bone-binding sites by calcium may reduce uptake of strontium-89 chloride.

These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

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Side Effects

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Dosage

Simethicone's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

20 to 40 mg30 (30)6 hourlyPOAfter Meals and at bedtime
40 to 80 mg60 (60)6 hourlyPO

Paedriatic Dosage (20kg)

0 to 20 mg10 (10)As recommended.POThis dose should be taken 4 times a day by children of 2-12 years of age.

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Simethicone is available.

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Simethicone

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