| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 0.625 to 2.5 mg/kg | 1.6 (1.5625) | As recommended. | | Lymphosarconas. |
| 7.5 mg | 7.5 (7.5) | As recommended. | | For Rheumatoid artheitis once weekly. |
| 12 mg/sq.meter | 22 (22) | As recommended. | Intra Thecal | Once a week |
| 2.5 mg/kg | 2.5 (2.5) | 24 hourly | IV | In leukemia every 14 days. |
| 10 to 25 mg/m2 | 18 (17.5) | As recommended. | PO | Breast cancer |
| 10 to 25 mg | 18 (17.5) | As recommended. | PO | Psoriasis (once a week) |
| 15 to 30 mg | 22 (22.5) | 24 hourly | PO,IM | For 5 days in prophylaxis of choriocarcinoma. |
Paedriatic Dosage (20kg)
|
| 5 to 15 mg/sq.meter | 10 (10) | As recommended. | Intra Muscular | Per Week for Rheum. Arthritis |
| 200 mg/sq.meter | 370 (367) | As recommended. | Intra Venous | For Induction |
| 1200 mg/sq.meter | 2200 (2199) | As recommended. | IV Infusion | Maintenance, Over 24 Hours |
| 5 to 15 mg/sq.meter | 10 (10) | As recommended. | Oral | Per Week for Rheum. Arthritis |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Methotrexate is available. |