Clofazimine
Overview
Clofazimine is a phenazine dye. Clofazimine is used in the treatment of leprosy. Clofazimine is usually used in combination with other anti-leprosy medication such as dapsone.A fat soluble riminophenazine dye used for treatment --- . it has been used investigationally in combination with other antimyobacterial drugs to treat mycokacterium avium infect in AIDS patients.Its has moved anti-inflamatory effect is given to control the leprosy reaction,erythma leprosum.
Categories
- 6 Anti-infective drugs
- 6.2 Antibiotics, systemic
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Drug Interactions
Clofazimine is known to interact with other drugs, the details of drug interactions is as follows:
Severity N/A
Rifampicin Interaction of Rifampicin with Clofazimine
Dapsone Interaction of Dapsone with Clofazimine
Rifampicin Interaction of Rifampicin with Clofazimine
These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
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Side Effects
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Dosage
Sulphurated Lime's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 50 to 300 mg/kg | 180 (175) | 24 hourly | PO | For multi bacillary. |
Paedriatic Dosage (20kg)
|
| 4.166 mg/kg | 4.2 (4.166) | As recommended. | Oral | Initially on alternate days |
| 8.333 mg/kg | 8.3 (8.333) | As recommended. | Oral | Maintenance per month |
Neonatal Dosage (3kg)
|
| 6.25 mg/kg | 6.2 (6.25) | 12 hourly | oral | Initial, weekly |
| 12.5 mg/kg | 12 (12.5) | As recommended. | oral | maintenance, monthly |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Sulphurated Lime
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