Pantoprazole

Overview

Pantoprazole is a proton pump inhibitor and causes long lasting inhibition of gastric acid secretion and used in the treatment of peptic ulcers. Chemically Pantoprazole is identified as 5-(difluoromethoxy)-2-[[(3,4-dimethyl-2-pyridinyl) methyl] sulfinyl]-1H-benzimidazole. Pantoprazole is a novel substituted benzimidazole sulfoxide derived prodrug similar to omeprazol and lansoprazol. Pantoprazole is administered orally.

Categories

Primary Characterstics

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

Pantoprazole is known to interact with other drugs, the details of drug interactions is as follows:

Severity N/A

Clarithromycin

Interaction of Clarithromycin with Pantoprazole

Details: Concurrent use may increase the risk of Pantoprazole side effects.
Warfarin (Na)

Interaction of Warfarin (Na) with Pantoprazole

Details: Pantoprazole may increase the risk of side effects of Warfarin (Na).
Digoxin

Interaction of Digoxin with Pantoprazole

Details: Pantoprazole may increase the risk of side effects of Warfarin (Na).
Ampicillin

Interaction of Ampicillin with Pantoprazole

Details: Pantoprazole may decrease the effectiveness of ampicillin.
Ketoconazole

Interaction of Ketoconazole with Pantoprazole

Details: Pantoprazole may decrease the effectiveness of Ketoconazole.
Clopidogrel

Interaction of Clopidogrel with Pantoprazole

Details: Pantoprazole may decrease the effectiveness of Clopidogrel.
Atazanavir

Interaction of Atazanavir with Pantoprazole

Details: Pantoprazole may decrease the effectiveness of Atazanavir.
Ceftibuten

Interaction of Ceftibuten with Pantoprazole

Dabrafenib

Interaction of Dabrafenib with Pantoprazole

Details: Proton pump inhibitors may alter the solubility of dabrafenib and reduce its bioavailability

These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

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Side Effects

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Dosage

Flurbiprofen's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage
0.571 mg/kg0.57 (0.571)24 hourlyPOFor 8 weeks

Paedriatic Dosage (20kg)
Not recommended for this age group

Neonatal Dosage (3kg)
No data regarding the neonatal dosage details of Flurbiprofen is available.

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Flurbiprofen

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