peginterferon alfa-2b
Overview
Categories
- 8 Antineoplastics, immunomodulators and drugs used in palliative care
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Peginterferon alfa-2b's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 1 to 1 mcg/kg/week | 1 (1) | As recommended. | Sc | Dose reduction or discontinuation is required in case of depression, haemtological and renal side effects. For patients with a history of stable cardiac disease receiving Pegnterferon alfa 2b in combination with ribavirin, dose should be reduced by half and the ribavirin dose by 200mg/day if a 2g/dL decrease in hemoglobin is observed during any 4 week period. Both Peginterferon alpha 2b and ribavirin should be permanently discontinued if patients have hemoglobin levels <12 g/dL after this ribavirin dose reduction. |
| 1.5 to 1.5 mcg/kg/week | 1.5 (1.5) | As recommended. | Sc | when it is used in combination with ribavirin. |
Paedriatic Dosage (20kg)
|
| 60 to 0 mcg/m2/week | 30 (30) | As recommended. | Sc | This is the dose when given in combination with ribavirin |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Peginterferon alfa-2b is available. |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Peginterferon alfa-2b
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Manufacturers of
peginterferon alfa-2b
in Pakistan
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