Immune Globulin

Overview

Immune Globulin is a concentrate of antibodies of human plasma. Immune Globulin is used to increase the immunity to some viral infections (like hepatitis, measles and rubella) and increases the body's natural immune response in persons with a compromised immune system and Immune Globulin is also used to increase blood count in persons with idiopathic thrombocytopenic purpura (decrease counts of platelets). Immune Globulin are produced by B lymphocytes in response to foriegn antigens.

Categories

• 19 Immunologicals
  • 19.2 Sera and gamma globulins
  • 19.2.4 Normal immunoglobulins (human)

Page headings

Primary Characterstics

Indications

Pharmacokinetics

Contraindications

Drug Interactions

Side Effects

The symptomatic adverse reactions produced by Immune Globulin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Fever, Myalgia, Chills, Urticaria, Erythema, Pain, Facial flushing, Flushing, Hypersensitivity, Angioedema, Tenderness, Muscle stiffiness.

Dosage

Immune Globulin's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
200 to 800 mg/kg	500 (500)	As recommended.		Every 3 to 4 weeks.
400 to 800 mg/kg	600 (600)	As recommended.	IV	Once in a Month or As Required. Then 200mg/kg every 3 to 4 week.
Paedriatic Dosage (20kg)
100 to 200 mg	150 (150)	As recommended.	IM	Once in a Month or As Required. Under 1 year or less children
Neonatal Dosage (3kg)
4 mg/kg	4 (4)	24 hourly	Intravenous	For 2---5 days

High Risk Groups

Warning / Precautions

Storage Conditions

Interference in Pathology

Brands / Trade Names of Immune Globulin

Manufacturers of Immune Globulin in Pakistan

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