Nisoldipine

Overview

Nisoldipine is a calcium-channel antagonist with actions and uses similar to those of nifedipine. It belongs to dihydropyridine class of calcium-channel antagonist that includes nifedipine, amlodipine, felodipine isradipine. In general, the dihydropyridine-type calcium-channel antagonists have more prominent effects on vasodilation and coronary flow than do diltiazem and verapamil. Nisoldipine is used in the treatment of Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon.

Categories

Primary Characterstics

Indications

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Pharmacokinetics

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Contraindications

Nisoldipine is contraindicated in conditions like Shock, Cardiac failure, Pulmonary hypertension, Aortic stenosis, Hepatic dysfunction, Hypersensitivity, Pregnancy, Lactation.

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Drug Interactions

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Side Effects

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Dosage

Nisoldipine's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

8.5 to 34 mg21 (21.25)24 hourlyPOFor Angina Pectoris Prophylaxis, Hypertension: Maintenance dose:
10 mg10 (10)24 hourlyPOFor Angina Pectoris Prophylaxis, Hypertension: Initial dose

Paedriatic Dosage (20kg)

No data regarding the Paedriatic dosage details of Nisoldipine is available.

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Nisoldipine is available.

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Nisoldipine

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Manufacturers of Nisoldipine in Pakistan

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