| 0.5 mg | 0.5 (0.5) | As recommended. | intravitreal | once a month (approximately 28 days). Although less effective, treatment may be reduced to one injection every three months after the first four injections if monthly injections are not feasible. Compared to continued monthly dosing, dosing every 3 months will lead to an approximate 5-letter (1-line) loss of visual acuity benefit, on average, over the following 9 months. Patients should be evaluated regularly. Adequate anesthesia and a broad-spectrum microbicide should be given prior to the intravitreal injection. |