| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 5 mg/kg | 5 (5) | 24 hourly | IV Induction | at 0, 2 and 6 weeks followed by a maintenance regimen of 5 mg/kg every 8 weeks (For Crohn's disease). For adult patients who respond and then lose their response, consideration may be given to treatment with 10 mg/kg. Patients who do not respond by Week 14 are unlikely to respond with continued dosing and consideration should be given to discontinue Infliximab in these patients. |
| 5 mg/kg | 5 (5) | 24 hourly | IV Induction | at 0, 2 and 6 weeks followed by a maintenance regimen of 5 mg/kg every 8 weeks thereafter for the treatment of moderately to severely active ulcerative colitis. |
| 3 mg/kg | 3 (3) | 24 hourly | IV Inf | followed with additional similar doses at 2 and 6 weeks after the first infusion then every 8 weeks thereafter. (for Rheumatoid Arthritis). For patients who have an incomplete response, consideration may be given to adjusting the dose up to 10 mg/kg or treating as often as every 4 weeks bearing in mind that risk of serious infections is increased at higher doses. |
| 5 mg/kg | 5 (5) | 24 hourly | IV Inf | followed with additional similar doses at 2 and 6 weeks after the first infusion, then every 6 weeks thereafter. (for Ankylosing Spondylitis) |
| 5 mg/kg | 5 (5) | 24 hourly | IV Inf | followed with additional similar doses at 2 and 6 weeks after the first infusion then every 8 weeks thereafter. (for Psoriatic Arthritis) |
| 5 mg/kg | 5 (5) | 24 hourly | IV Inf | followed with additional similar doses at 2 and 6 weeks after the first infusion then every 8 weeks thereafter. (for Plaque Psoriasis) |
Paedriatic Dosage (20kg)
|
| 5 mg/kg | 5 (5) | As recommended. | IV infusion | Followed by additional 5mg/kg infusion doses at 2 & 6 weeks. |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Infliximab is available. |