Dosage
Irinotecan (HCl Trihydrate)'s dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 100 to 200 mg | 150 (150) | 24 hourly | PO | This is the dose for mild condition. |
| 700 to 900 mg | 800 (800) | As recommended. | PO | This is the dose for sever condition. Doses above 300mg/day should be given in divided doses. |
| 300 to 600 mg | 450 (450) | As recommended. | PO | This is the dose for moderately sever condition; give in divided doses. |
Paedriatic Dosage (20kg)
|
| 10 to 20 mg/kg/day | 15 (15) | As recommended. | Oral | For under 15 years of age: maximum 400 mg/day in neoplastic condition, enzymes disorder. |
Neonatal Dosage (3kg)
|
| 10 to 20 mg/kg | 15 (15) | 24 hourly | oral | |